Small ubiquitin-related modifier 2

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August undefined, 2024

WebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, -2, -3, and -4) belong to the group of ubiquitin-like protein-modifying enzymes. Similarly to ubiquitination, SUMOylation is a multistep process that involves an ... WebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Small ubiquitin-related modifier 2/3 interacts with p65 and …

WebAbstract. Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking ... WebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, … birth certificate gro

Small ubiquitin-related modifier 2 (tropical clawed frog)

WebOct 12, 2015 · The mouse small ubiquitin-like modifier-2 (SUMO-2) inhibits interleukin-12 (IL-12) production in mature dendritic cells by blocking the translocation of the p65 subunit … WebSUMO (small ubiquitin-related modifier) proteins are ∼ 10-kD polypeptides that function as reversible post-translational protein modifiers. They form isopeptide bonds with ɛ-amino … WebSmall ubiquitin-related modifier 1, 2 and 3 (SUMO-1, -2 and -3) are members of the ubiquitin-like protein family (1). The covalent attachment of the SUMO-1, -2 or -3 (SUMOylation) to target proteins is analogous to … daniel filipovic thunder bay

Mapping of SUMO sites and analysis of SUMOylation changes ... - PNAS

Hepatic Small Ubiquitin‐Related Modifier …

WebOverview Product name Anti-Sumo 2 + Sumo 3 antibody See all Sumo 2 + Sumo 3 primary antibodies Description Rabbit polyclonal to Sumo 2 + Sumo 3 Host species Rabbit Specificity Recognises 2 bands representing Sumo 2 and Sumo 3 at 15 and 18kDa in Hela Nuclear extract by Western blotting. Tested applications In molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. This process is called SUMOylation (sometimes written sumoylation). SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional re… daniel files levittown paWebMay 1, 2009 · The present study aimed to produce and pathophysiologically evaluate the metallothionein (MT) fusion protein. A recombinant plasmid containing DNA segment coding the pET-glutathione transferase (GST)-small ubiquitin-related modifier (SUMO)-MT fusion protein was inserted into Escherichia coli for expression. The expression level of … daniel fields tp icap

"WebSUMOylation by generating mature small ubiquitin-related modifiers (SUMO) for protein conjugation (endopeptidase ... SUMO protease but functions on another small ubiquitin-re-latedproteinknownasNedd8(6,7).Thedefiningcharacteristic ... SUMO, small ubiquitin-like modifier; AFC, 7-amino-4-trifluoromethyl coumarin; DUB, de-ubiquitinating enzyme; " - Small ubiquitin-related modifier 2

Small ubiquitin-related modifier 2

Small Ubiquitin-related Modifier (SUMO)-specific Proteases

WebMay 2, 2024 · Small ubiquitin-related modifier (SUMO)–specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, … WebSep 29, 2024 · Small ubiquitin-related modifier (SUMO) is one such modifier. Therefore, ubiquitination and sumoylation are two post-translational modifications. Ubiquitination marks proteins for degradation. In contrast, sumoylation is not used to mark proteins for degradation. Both modifications regulate protein localization and activity.

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WebSep 23, 2004 · Covalent attachment of small proteins to substrates can regulate protein activity in eukaryotes. SUMO, the s mall u biquitin-related mo difier, can be covalently linked to a broad spectrum of substrates. An understanding of …

WebApr 13, 2024 · Tumor cells are known to produce high amounts of intracellular lipids, leading to increased levels of fatty acids, cholesterol and membrane phospholipids. Death domain-associated protein (DAXX) is a small ubiquitin-related modifier (SUMO)-binding protein that plays a role in transcription regulation by interacting with transcription factors such as … WebSUMOylation by generating mature small ubiquitin-related modifiers (SUMO) for protein conjugation (endopeptidase activity)andremovingconjugatedSUMOfromtargets(isopep …

WebSmall ubiquitin-related modifier (SUMO)-specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, signal transduction, … WebOct 1, 2024 · Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates multiple biological processes, including cell division, DNA …

WebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in …

WebSmall ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. [5] Function [ edit] This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. daniel fesler companywebUniProt P61956 · SUMO2_HUMAN Protein Small ubiquitin-related modifier 2 Gene SUMO2 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 95 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST … See more This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. 1. Name1 2. See … See more daniel field hair colour reviewsWebJul 26, 2024 · together, this work shows that small ubiquitin-related modifier-2 modification of NF-jB2/p65 is essential for the survival of Brucella abortus 2308 inside macrophages. … daniel field organic hair colourWebJun 4, 2024 · Ubiquitin is a small (8.6 kDa) 76-residue regulatory protein which is found ‘ubiquitously’ in the cytoplasm and nucleus of eukaryotic cells and is a post-translational … birth certificate gurugramWebSmall ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma. Data show that substantial increases in the … daniel filmus twitterWebFeb 22, 2005 · Importantly, Sp100 and PML are both covalently linked to small ubiquitin-related modifiers (SUMOs). Therefore, we investigated whether SUMO proteins are independent autoantigens in PBC and studied 99 PBC sera samples for reactivity against NDs, PML, and Sp100, as well as against SUMO-2 and SUMO-1 recombinant proteins. daniel findley fbc keystone heightsWebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, -2, -3, and -4) belong to the group of ubiquitin-like protein-modifying enzymes. Similarly to ubiquitination, SUMOylation is a multistep process that involves an ... daniel finch ocean winds